Answer :
hello!
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Plug in the values of the variables & simplify:-
[tex]\longrightarrow\pmb{4x^2y^2}[/tex]
The values of the variables are:-
[tex]\bigstar{\boxed{x=2~and~y=-2}[/tex]
Simplify:-
[tex]\longrightarrow\pmb{4(2)^2(-2)^2}[/tex]
[tex]\longrightarrow\pmb{4*4-4}[/tex]
[tex]\longrightarrow\pmb{16-4}[/tex]
[tex]\longrightarrow\pmb{12}[/tex]
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note:-
Hope everything is clear; if you need any clarification/explanation, kindly let me know, and I'll comment and/or edit my answer :)