57BWFJ8SS8IN 57BWFJ8SS8IN Biology Answered 4. Why are well-defined reading frames critical in protein synthesis? O A. Without a well-defined reading frame, the ribosome is unable to bind to the mRNA. OB. Without a well-defined reading frame, the peptide made from a given sequence could be completely different. O C. Without a well-defined reading frame, the resulting protein would be transported to the cell surface. O D. Without a well-defined reading frame, the mRNA would be transcribed back into DNA.